|
Symbol Name ID |
Hk1
hexokinase 1 MGI:96103 |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating IgA level |
Increased circulating IgG level |
Decreased circulating antibody level |
Paraproteinemia |
Reticulocytosis |
Anemia |
Fava bean-induced hemolytic anemia |
Nonspherocytic hemolytic anemia |
Spontaneous hemolytic crises |
Anisocytosis |
Heinz bodies |
Poikilocytosis |
Leukocytosis |
Impaired neutrophil bactericidal activity |
Acute lymphoblastic leukemia |
T-cell acute lymphoblastic leukemias |
Lymphoma |
Multiple myeloma |
Splenomegaly |
| Disease(s) Associated with HK1 | |||||||||||||||||||
| acute lymphoblastic leukemia | |||||||||||||||||||
| congenital nonspherocytic hemolytic anemia | |||||||||||||||||||
| multiple myeloma |
| Mouse Phenotypes | increased spleen weight |
abnormal erythropoiesis |
anemia |
hemolytic anemia |
abnormal erythrocyte morphology |
decreased erythrocyte cell number |
decreased hematocrit |
decreased hemoglobin content |
decreased mean corpuscular hemoglobin |
increased mean corpuscular volume |
anisocytosis |
hyperchromasia |
polychromatophilia |
reticulocytosis |
abnormal spleen morphology |
increased spleen red pulp amount |
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| Availability | Mouse Genotype | ||||||||||||||||
| Hk1dea/Hk1dea | |||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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